Brain diseases are an increasing global health burden in the Western world, especially due to our ageing population. Stroke is the second most common cause of death worldwide. Brain tumors are among the most deadly types of cancer. Neurodegenerative diseases are rising due to our aging population. The World Health Organization (WHO) predicted that by 2050, 30 million people will be affected by Alzheimer's disease in Europe and the USA alone. Other neurodegenerative diseases such as Small Vessel Disease, Multiple sclerosis, Parkinson's disease, Huntington's disease, and dementia exert an increasing toll on the population.
Technical advancements in medical imaging have made it possible to study the brain in detail, to detect these diseases at an early stage, to learn more about the nature of these degenerative diseases and to follow the course of these diseases over time. MRI scanners with higher field strengths are generating images at a very fine resolution. New scanning sequences make it possible to study the brain's structure in detail, to measure brain function, or even analyze the connectivity within the brain. However, at the same time, this explosion of available information makes it increasingly cumbersome for clinicians and researchers to interpret these images. CT has the advantage that it can image rapidly, with high resolution and is more widely available than MRI. Worldwide, MRI and CT brain scans are made in roughly equal numbers. With both modalities, DIAG research focuses on the analysis of perfusion scans, 4D series that imagine the in and outflow of blood in the brain.